CJC-1295 (No DAC)
GHRH analogue fragment — studied for growth hormone secretagogue effects.
Purity
98%+ (per source specifications)
Form
Lyophilised Powder
Storage
-20°C lyophilised · store at 2–8°C once reconstituted
£24.99
Free UK delivery
About CJC-1295 (No DAC)
What it is
CJC-1295 without DAC, also called Mod GRF (1-29), is a modified fragment of growth-hormone-releasing hormone. Four amino acid substitutions protect it from the enzyme that rapidly degrades the natural molecule, extending its useful life from minutes to something workable in an experiment.
How it is understood to work
It binds the GHRH receptor on pituitary cells. The "No DAC" distinction matters: the DAC version carries a Drug Affinity Complex that binds serum albumin and extends half-life to days, whereas this one does not, giving a much shorter and sharper profile. Those are meaningfully different research tools and should not be treated as interchangeable.
What research has looked at
Receptor-binding work and pituitary cell culture examining release kinetics.
Handling and storage
Short half-life in solution relative to the DAC form. Reconstitute what you need, keep it cold, and do not expect it to hold indefinitely.
Supplied for in-vitro laboratory research only. Nothing above describes a dose, a protocol, or a use in humans or animals, and none of these compounds is a licensed medicine in the UK.
Certificate of Analysis
Purity (HPLC)
99.7%
- Batch
- 800028-26031301
| Test | Specification | Result |
|---|---|---|
| Appearance | White powder | White powder |
| Identity (mass spectrometry) | 3367.9 ± 1.0 | 3368.0 |
| Purity (HPLC) | Not less than 98.0% | 99.7% |
| Bacterial endotoxins | Not more than 10 EU/mg | Conforms |
| Water content (Karl Fischer) | Not more than 8.0% | 4.3% |
| Residual solvents | Within limits | Conforms |
This batch of CJC-1295 (No DAC) complies with specification. Figures are taken from the manufacturer certificate of analysis for this batch.
Research Information
CJC-1295 (No DAC) is a synthetic 30-amino-acid analogue of growth hormone releasing hormone (GHRH), studied for its role in pituitary research. The "No DAC" designation means it lacks the Drug Affinity Complex modification, giving it a shorter half-life and making it a closer reference compound for studying native GHRH activity. Researchers are interested in how it interacts with the GHRH receptor in pituitary cell models and its effects on downstream growth hormone signalling.
Research areas
- GHRH receptor (GHRHR) binding studies
- Pituitary cell-line research
- Native vs modified GHRH analogue comparison
- Growth hormone release pathway studies
Analytical methods
Identity and purity are typically confirmed at source by high-performance liquid chromatography (HPLC) and mass spectrometry.
Storage and handling
Store lyophilised at -20°C, away from moisture and direct light. Once reconstituted, store at 2–8°C and use within the timeframe specified on the source datasheet.
For Research Use Only. Not for human or veterinary use.
Batch tested
Every batch is tested for identity and purity, and we publish the certificate.
UK dispatch
UK-stocked. Orders placed before 2pm dispatch the same business day via Royal Mail Tracked 24. Free UK shipping on every order. We ship to UK addresses only.